The game against the Durban-based Sharks replaces the scheduled Tour match against the Bulls and is the third in an eight-game Series culminating in the three Tests against World Champions, the Springboks.
This is the second time the Lions will have played the Sharks in the Castle Lager Lions Series, having already beaten them 7-54 on Wednesday night at Emirates Airline Park.
“It’s obviously been a slightly turbulent week, but we remain determined to keep rolling with the punches,” said Gatland.
“In many ways, the challenges we’ve faced this week have strengthened our resolve to do everything we can to overcome the challenges created by covid.
“The feeling in the camp on Wednesday night was just to give it a crack – I was really proud by how everyone reacted, particularly the match day squad who would have never prepared for a game like that before.
“Saturday is another opportunity to see how the boys go and for us as coaches to try out a few more combinations ahead of the Test series.
“I have long been an admirer of Jamie’s leadership skills, so I am delighted to name him skipper.
“We want to pass on thanks to the Sharks boys for fronting up and going again on Saturday. The spirit of rugby and a great chance for them to have another shot at us.”
British & Irish Lions:
15. Liam Williams (Scarlets, Wales) #833
14. Anthony Watson (Bath Rugby, England) #816
13. Elliot Daly (Saracens, England) #822
12. Chris Harris (Gloucester Rugby, Scotland) #844
11. Duhan van der Merwe (Worcester Warriors, Scotland) #841
10. Dan Biggar (Northampton Saints, Wales) #821
9. Gareth Davies (Scarlets, Wales) #850
8. Jack Conan (Leinster Rugby, Ireland) #839
7. Hamish Watson (Edinburgh Rugby, Scotland) #847
6. Tadhg Beirne (Munster Rugby, Ireland) #838
5. Jonny Hill (Exeter Chiefs, England) #845
4. Maro Itoje (Saracens, England) #825
3. Tadhg Furlong (Leinster Rugby, Ireland) #818
2. Jamie George – captain (Saracens, England) #819
1. Rory Sutherland (Worcester Warriors, Scotland) #840.
16. Ken Owens (Scarlets, Wales) #829
17. Wyn Jones (Scarlets, Wales) #842
18. Kyle Sinckler (Bristol Bears, England) #814
19. Courtney Lawes (Northampton Saints, England) #826
20. Sam Simmonds (Exeter Chiefs, England) #849
21. Tom Curry (Sale Sharks, England) #853
22. Conor Murray (Munster Rugby, Ireland) #790
23. Finn Russell (Racing 92, Scotland) #835